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Table 1 Clinical characteristics of patients with hypergammaglobulinemia

From: Hypergammaglobulinemia in the pediatric population as a marker for underlying autoimmune disease: a retrospective cohort study

 

Total

Autoimmune

Infection

Malignancy

PID

Drug

Other

n = 442

n = 221

n = 163

n = 10

n = 15

n = 9

n = 25

Median age, years

14.3

13.8

14.8

13.2

13.7

16.6

13.8

Female, n (%)

228 (63)

168 (76)

80 (49)

2 (20)

11 (73)

5 (56)

12 (48)

Race/ethnicity, n (%)

       

  White

229 (52)

95 (43)

107 (66)

5 (50)

6 (40)

8 (89)

8 (32)

  Black

81 (18)

49 (22)

24 (15)

2 (20)

0 (0)

0 (0)

7 (28)

  Hispanic

31 (7)

19 (9)

9 (6)

1 (10)

0 (0)

0 (0)

2 (8)

  Asian

26 (6)

13 (6)

6 (4)

1 (10)

3 (20)

0 (0)

3 (12)

  Other/unknown

75 (17)

44 (20)

17 (10.6)

2 (20)

6 (40)

1 (17)

5 (20)

Median follow-up period, years

2.9

3.3

3.0

3.5

2.6

0.5

2.0

Death during follow-up period, n (%)

42 (10)

6 (3)

30 (18)

3 (30)

1 (7)

0 (0)

1 (4)

  1. PID primary immunodeficiency.