Table 2 Results of case-control association of PTPN22, MIF and TNFA variants among JIA sub-phenotypes
| Â | PTPN22 | MIF | TNFA G-238A | TNFA G-308A | ||||
|---|---|---|---|---|---|---|---|---|
Subtype | # Cases | OR (95% CI) | # Cases | OR (95% CI) | # Cases | OR (95% CI) | # Cases | OR (95% CI) |
Systemic | 50 | 1.06 (0.53, 1.91) | 49 | 1.53 (0.93, 2.45) | 50 | 1.69 (0.76, 3.36) | 50 | 0.33 (0.13, 0.69) 4 |
RF-Positive | 48 | 2.12 (1.24, 3.49) 1 | 47 | 1.06 (0.60, 1.75) | 48 | * | 47 | 0.98 (0.54, 1.66) |
RF-Negative | 154 | 1.09 (0.74, 1.57) | 158 | 0.86 (0.61, 1.19) | 157 | 1.14 (0.67, 1.86) | 156 | 0.85 (0.60, 1.18) |
ERA | 55 | 1.09 (0.55, 1.97) | 56 | 1.23 (0.74, 1.98) | 56 | 0.94 (0.35, 2.06) | 56 | 0.40 (0.18, 0.78) 5 |
Oligoarticular | 284 | 1.35 (1.01, 1.80) 2 | 283 | 1.06 (0.83, 1.36) | 284 | 0.33 (0.16, 0.59) 3 | 276 | 0.96 (0.73, 1.25) |