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Table 3 Haematological variables and lymphocyte populations in children with the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA) and children with pneumonia (Pn)

From: Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system

  Pn-nf p-value PFAPA-nf p-value PFAPA-f p-value Pn-f
   Pn-nf   PFAPA-nf   PFAPA-f  
   vs   vs   vs  
   PFAPA-nf   PFAPA-f   Pn-f  
  (n=10)   (n= 21) (n=13) (n=14)   (n=14/12*)
White blood cells (109/L) 9.2 ns 7.9 0.003 13.3 ns 14.7
(6.1, 11.4)   (5.7, 10.1)   (9.4, 15.2)   (10.5, 19.2)
Neutrophils (109/L) 3.15 ns 3.2 0.002 9.2 ns 9.1
(2.3, 5.6)   (2.5,4.1)   (5.8, 11.8)   (5.0, 14.7)
Thrombocytes (109/L) 366 ns 355 ns 299 ns 385
(289, 413)   (296, 427)   (269, 353)   (275, 482)
Lymphocytes (109/L) 3.95 ns 3.0 0.004 2.3 0.006 3.8
(2.5, 4.8)   (2.4, 4.4)   (1.5,3.1)   (2.5, 4.6)
Monocytes (109/L) 0.7 ns 0.6 0.002 1.4 ns 1.3
(0.5, 0.8)   (0.6, 0.8)   (1.2, 1.8)   (1.1, 1.6)
Eosinophils (109/L) 0.2 ns 0.2 0.002 0.0 0.009 0.2
(0.1, 0.5)   (0.1, 0.4)   (0.0, 0.1)   (0.03, 0.3)
  (n=9)   (n=15) (n=8) (n=8)   (n=10)
CD3 (106/L) 2583 ns 2527 0.012 1087 0.021 2145
(1744, 3098)   (1998, 3006)   (894, 1592)   (1211, 3368)
CD4 (106/L) 1294 ns 1478 0.017 698 0.041 1310
(1034, 1619)   (1025, 1909)   (494, 1062)   (765, 2006)
CD8 (106/L) 1196 ns 891 0.012 359 0.010 801
(655, 1325)   (658, 1022)   (254, 420)   (399, 1084)
CD56 (106/L) 253 ns 414 ns 203 ns 172
(193, 354)   (224, 590)   (116, 329)   (62.5, 303)
CD19 (106/L) 629 ns 596 ns 574 ns 991
  (403, 880)   (430, 1247)   (346, 823)   (393, 1109)
  1. Results are given as median (quartiles).
  2. Pn-nf: Children with pneumonia after complete remission.
  3. PFAPA-nf: Children with PFAPA between febrile episodes.
  4. PFAPA-f: Children with PFAPA during febrile episodes.
  5. Pn-f: Children with pneumonia shortly after admission.
  6. ns: not significant.
  7. * Lymphocytes, monocytes and eosinophils were measured in 12 children with Pn-f.
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Pediatric Rheumatology

ISSN: 1546-0096