Skip to main content

Table 3 Haematological variables and lymphocyte populations in children with the periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis syndrome (PFAPA) and children with pneumonia (Pn)

From: Elevated levels of CXCL10 in the Periodic Fever, Aphthous stomatitis, Pharyngitis and cervical Adenitis syndrome (PFAPA) during and between febrile episodes; an indication of a persistent activation of the innate immune system

 

Pn-nf

p-value

PFAPA-nf

p-value

PFAPA-f

p-value

Pn-f

  

Pn-nf

 

PFAPA-nf

 

PFAPA-f

 
  

vs

 

vs

 

vs

 
  

PFAPA-nf

 

PFAPA-f

 

Pn-f

 
 

(n=10)

 

(n= 21)

(n=13)

(n=14)

 

(n=14/12*)

White blood cells (109/L)

9.2

ns

7.9

0.003

13.3

ns

14.7

(6.1, 11.4)

 

(5.7, 10.1)

 

(9.4, 15.2)

 

(10.5, 19.2)

Neutrophils (109/L)

3.15

ns

3.2

0.002

9.2

ns

9.1

(2.3, 5.6)

 

(2.5,4.1)

 

(5.8, 11.8)

 

(5.0, 14.7)

Thrombocytes (109/L)

366

ns

355

ns

299

ns

385

(289, 413)

 

(296, 427)

 

(269, 353)

 

(275, 482)

Lymphocytes (109/L)

3.95

ns

3.0

0.004

2.3

0.006

3.8

(2.5, 4.8)

 

(2.4, 4.4)

 

(1.5,3.1)

 

(2.5, 4.6)

Monocytes (109/L)

0.7

ns

0.6

0.002

1.4

ns

1.3

(0.5, 0.8)

 

(0.6, 0.8)

 

(1.2, 1.8)

 

(1.1, 1.6)

Eosinophils (109/L)

0.2

ns

0.2

0.002

0.0

0.009

0.2

(0.1, 0.5)

 

(0.1, 0.4)

 

(0.0, 0.1)

 

(0.03, 0.3)

 

(n=9)

 

(n=15)

(n=8)

(n=8)

 

(n=10)

CD3 (106/L)

2583

ns

2527

0.012

1087

0.021

2145

(1744, 3098)

 

(1998, 3006)

 

(894, 1592)

 

(1211, 3368)

CD4 (106/L)

1294

ns

1478

0.017

698

0.041

1310

(1034, 1619)

 

(1025, 1909)

 

(494, 1062)

 

(765, 2006)

CD8 (106/L)

1196

ns

891

0.012

359

0.010

801

(655, 1325)

 

(658, 1022)

 

(254, 420)

 

(399, 1084)

CD56 (106/L)

253

ns

414

ns

203

ns

172

(193, 354)

 

(224, 590)

 

(116, 329)

 

(62.5, 303)

CD19 (106/L)

629

ns

596

ns

574

ns

991

 

(403, 880)

 

(430, 1247)

 

(346, 823)

 

(393, 1109)

  1. Results are given as median (quartiles).
  2. Pn-nf: Children with pneumonia after complete remission.
  3. PFAPA-nf: Children with PFAPA between febrile episodes.
  4. PFAPA-f: Children with PFAPA during febrile episodes.
  5. Pn-f: Children with pneumonia shortly after admission.
  6. ns: not significant.
  7. * Lymphocytes, monocytes and eosinophils were measured in 12 children with Pn-f.