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Table 2 Overall effects of exercise training (groups combined n=25)

From: Exercise in children with joint hypermobility syndrome and knee pain: a randomised controlled trial comparing exercise into hypermobile versus neutral knee extension

Outcome measure Baseline mean (SD) Post-treatment mean (SD) Post-treatment –baseline P value Cohen’s D
    Difference between means Lower bound of 95% CI Upper bound of 95% CI   
Primary Outcome Measures
Child’s report of mean knee pain over the week 1 39.4(14.2) 24.2 (18.4) −14.5 −5.2 −23.8 0.004* 0.89
Child’s report of maximum knee pain over the week 1 55.5(18.8) 37.4 (27.5) −18.1 −6.7 −29.4 0.003* 0.78
Secondary Outcome Measures
Child Reported Measures
PGIC2 .23 (1.04) 1.77 (.91) 1.53 1.03 2.04 <0.001* 1.57
CHAQ 383 −0.05 (0.57) 0.02 (0.66) 0.066 −0.11 0.24 0.433 0.11
Physical Measures
Overall thigh strength (N) 4.19 (2.02) 5.25 (1.99) 1.06 0.39 1.72 0.004* 0.53
No. of flights of stairs ran in 2 minutes 18.6 (5.73) 20.33 (5.49) 1.73 −0.48 3.94 0.11 0.29
Parent Reported Measures (CHQ-PF50) 4
Physical Summary Score 37.97 (12.56) 43.31 (11.26) 5.34 1.73 8.94 0.002* 0.45
Psychosocial summary score 48 (10.25) 50.73 (11) 2.73 −0.33 5.8 0.03* 0.26
  1. 1 Using 2 separate 0 - 100 mm VAS’s, a higher score depicts more pain.
  2. 2 Patient’s Global Impression of Change (PGIC).
  3. 3 Child Health Assessment Questionnaire – 38 question version (CHAQ-38).
  4. 4 Child Health Questionnaire (CHQ).
  5. *p<0.05 statistically significant.