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Table 2 MVK SNPs investigated for association in the US cohort

From: Autoinflammatory gene polymorphisms and susceptibility to UK juvenile idiopathic arthritis

SNP CHR Position Gene Major allele (allele 1) Minor allele (allele 2) MAF Case MAF Control pHWE Control Case genotype frequencies Control genotype frequencies   Odds ratio 95% CI
1/1 (%) 1/2 (%) 2/2 (%) 1/1 (%) 1/2 (%) 2/2 (%) p-value
rs888193* 12 109987576 MVK G C 0.25 0.26 0.22 450 313 41 1679 1148 220 0.22 0.92
(56.0) (38.9) (5.1) (55.1) (37.7) (7.2) 0.81-1.05
rs7957619 12 110013879 MVK G A 0.10 0.12 0.67 653 150 9 2358 650 48 0.04 0.83
(80.4) (18.5) (1.1) (77.2) (21.3) (1.6) 0.7-0.99
  1. * rs888193 is a perfect proxy (r2=1) for rs11836136.
  2. CHR=chromosome, MAF=minor allele frequency, CI=confidence interval, pHWE=p-value for departure from Hardy-Weinburg equilibrium.