|
Characteristic
|
Flared (5)
|
Time to flare median (days)
|
p-value**
|
|---|
|
Joint
| | | |
|
Knee (n=112
|
55 (49.1)
|
972.0
| |
|
Ankle (n=30)
|
12 (39.9)
|
903
|
0.0297†
|
|
Wrist (n=17)
|
11 (64.7)
|
569.0
| |
|
Elbow (m=14)
|
2 (14.3)
|
243
| |
|
Diagnosis
| | | |
|
Oligoarthritis (n=97)
|
39 (40.2)
|
1042.0
| |
|
Polyarthritis (n=40)
|
15 (37.5)
|
903.0
| |
|
Extended oligoarthritis (n=23)
|
14 (60.9)
|
569.0
|
0.0003††
|
|
Systemic arthritis (n=14)
|
11 (78.6)
|
276.0
| |
|
Enthesits-related arthritis (n=6)
|
3 (50.0)
|
629.0
| |
|
Psoriatic arthritis (n=2)
|
1 (50.0)
|
797.0*
| |
|
Medications
| | | |
|
DMARD
| | | |
|
No (n=116)
|
53 (45.7)
|
846.0
|
0.8660
|
|
Yes (n=68)
|
32 (47.1)
|
903.0
| |
|
Biologics
| | | |
|
No (n=141)
|
64 (44.4)
|
972.0
|
0.0729
|
|
Yes (n=43)
|
21 (48.8)
|
615.0
| |
|
NSAID
| | | |
|
No (n=84)
|
42 (50.0)
|
797.0
|
0.1353
|
|
Yes (n=100)
|
43 (43.0)
|
972.0
| |
- *Median not estimated by SAS; the reported value is the 25th percentile.
- **p-value<0.05 was considered statistically significant.
- †A significant difference between joint types was found for elbow vs. wriset joint (p=0.0180) after adjusting for multiple testing using a Hochberg procedure.
- ††A significant difference between JIA subtypes was found for oligoarthritis vs. systemic arthritis (p=0.0015) and between polyarthritis vs. systemic arthritis (p=0.0084) after adjusting for multiple testing using Hochberg procedure.
