Durability of response to intra-articular corticosteroid injections with triamcinolone hexacetonide in juvenile idiopathic arthritis

Table 1 Factors affecting flare in JIA patients post-ICAI (n=184)

Characteristic	Flared (5)	Time to flare median (days)	p-value**
Joint
Knee (n=112	55 (49.1)	972.0
Ankle (n=30)	12 (39.9)	903	0.0297†
Wrist (n=17)	11 (64.7)	569.0
Elbow (m=14)	2 (14.3)	243
Diagnosis
Oligoarthritis (n=97)	39 (40.2)	1042.0
Polyarthritis (n=40)	15 (37.5)	903.0
Extended oligoarthritis (n=23)	14 (60.9)	569.0	0.0003††
Systemic arthritis (n=14)	11 (78.6)	276.0
Enthesits-related arthritis (n=6)	3 (50.0)	629.0
Psoriatic arthritis (n=2)	1 (50.0)	797.0*
Medications
DMARD
No (n=116)	53 (45.7)	846.0	0.8660
Yes (n=68)	32 (47.1)	903.0
Biologics
No (n=141)	64 (44.4)	972.0	0.0729
Yes (n=43)	21 (48.8)	615.0
NSAID
No (n=84)	42 (50.0)	797.0	0.1353
Yes (n=100)	43 (43.0)	972.0

*Median not estimated by SAS; the reported value is the 25^th percentile.
**p-value<0.05 was considered statistically significant.
†A significant difference between joint types was found for elbow vs. wriset joint (p=0.0180) after adjusting for multiple testing using a Hochberg procedure.
††A significant difference between JIA subtypes was found for oligoarthritis vs. systemic arthritis (p=0.0015) and between polyarthritis vs. systemic arthritis (p=0.0084) after adjusting for multiple testing using Hochberg procedure.

ISSN: 1546-0096