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Table 1 Factors affecting flare in JIA patients post-ICAI (n=184)

From: Durability of response to intra-articular corticosteroid injections with triamcinolone hexacetonide in juvenile idiopathic arthritis

Characteristic Flared (5) Time to flare median (days) p-value**
Joint    
Knee (n=112 55 (49.1) 972.0  
Ankle (n=30) 12 (39.9) 903 0.0297†
Wrist (n=17) 11 (64.7) 569.0  
Elbow (m=14) 2 (14.3) 243  
Diagnosis    
Oligoarthritis (n=97) 39 (40.2) 1042.0  
Polyarthritis (n=40) 15 (37.5) 903.0  
Extended oligoarthritis (n=23) 14 (60.9) 569.0 0.0003††
Systemic arthritis (n=14) 11 (78.6) 276.0  
Enthesits-related arthritis (n=6) 3 (50.0) 629.0  
Psoriatic arthritis (n=2) 1 (50.0) 797.0*  
Medications    
DMARD    
No (n=116) 53 (45.7) 846.0 0.8660
Yes (n=68) 32 (47.1) 903.0  
Biologics    
No (n=141) 64 (44.4) 972.0 0.0729
Yes (n=43) 21 (48.8) 615.0  
NSAID    
No (n=84) 42 (50.0) 797.0 0.1353
Yes (n=100) 43 (43.0) 972.0  
  1. *Median not estimated by SAS; the reported value is the 25th percentile.
  2. **p-value<0.05 was considered statistically significant.
  3. †A significant difference between joint types was found for elbow vs. wriset joint (p=0.0180) after adjusting for multiple testing using a Hochberg procedure.
  4. ††A significant difference between JIA subtypes was found for oligoarthritis vs. systemic arthritis (p=0.0015) and between polyarthritis vs. systemic arthritis (p=0.0084) after adjusting for multiple testing using Hochberg procedure.