Skip to main content

Table 1 Comparison of the features of the ILAR and Yamaguchi criteria

From: Application of the Yamaguchi criteria for classification of “suspected” systemic juvenile idiopathic arthritis (sJIA)

ILAR criteria[3] Yamaguchi criteria[10]
Arthritis in one or more joints with, or preceded by Daily fever of at least 2 weeks duration, that is documented to be quotidian for at least 3 days, and accompanied by one or more of the following Major criteria
1. Evanescent (non-fixed) erythematous rash 1) Fever of 39C or higher lasting 1 week or longer
2. Generalized lymph node enlargement 2) Arthralgia lasting 2 weeks or longer
3. Hepatomegaly and/or splenomegaly 3) Typical rash $
4. Serositis 4) Leukocytosis (10,000/cmm or greater) including 80% or more of granulocytes
Minor criteria
1.) Sore throat
2. ) Lymphadenoapthy and/or splenomegaly
3.) Liver dysfunction
4.) Negative Rheumatoid Factor (RF) and negative Antinuclear antibody (ANA) test
Diagnosis is made when there are 5 or more criteria which include atleast 2 major criteria.
Exclusions:- Exclusions
a. Psoriasis or a history of psoriasis in the patient or first degree relative 1.) Infections
b. Arthritis in an HLA B27-positive male beginning after the 6th birthday 2.) Malignancies
c. Ankylosing spondylitis, enthesitis related arthritis, sacroiliitis with inflammatory bowel disease, Reiter’s syndrome, or acute anterior uveitis, or a history of one of these disorders in a first degree relative 3.) Rheumatic diseases
d. The presence of IgM rheumatoid factor on at least 2 occasions at least 3 months apart.  
  1. $ Typical rash = Nonpruritic macular or maculopapular salmon colored rash (usually over trunk or extremities while febrile).