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Table 1 Comparison of the features of the ILAR and Yamaguchi criteria

From: Application of the Yamaguchi criteria for classification of “suspected” systemic juvenile idiopathic arthritis (sJIA)

ILAR criteria[3]

Yamaguchi criteria[10]

Arthritis in one or more joints with, or preceded by Daily fever of at least 2 weeks duration, that is documented to be quotidian for at least 3 days, and accompanied by one or more of the following

Major criteria

1. Evanescent (non-fixed) erythematous rash

1) Fever of 39C or higher lasting 1 week or longer

2. Generalized lymph node enlargement

2) Arthralgia lasting 2 weeks or longer

3. Hepatomegaly and/or splenomegaly

3) Typical rash $

4. Serositis

4) Leukocytosis (10,000/cmm or greater) including 80% or more of granulocytes

Minor criteria

1.) Sore throat

2. ) Lymphadenoapthy and/or splenomegaly

3.) Liver dysfunction

4.) Negative Rheumatoid Factor (RF) and negative Antinuclear antibody (ANA) test

Diagnosis is made when there are 5 or more criteria which include atleast 2 major criteria.



a. Psoriasis or a history of psoriasis in the patient or first degree relative

1.) Infections

b. Arthritis in an HLA B27-positive male beginning after the 6th birthday

2.) Malignancies

c. Ankylosing spondylitis, enthesitis related arthritis, sacroiliitis with inflammatory bowel disease, Reiter’s syndrome, or acute anterior uveitis, or a history of one of these disorders in a first degree relative

3.) Rheumatic diseases

d. The presence of IgM rheumatoid factor on at least 2 occasions at least 3 months apart.

  1. $ Typical rash = Nonpruritic macular or maculopapular salmon colored rash (usually over trunk or extremities while febrile).