Figure 1

Liver biopsy at nine weeks consistent with Alagille syndrome. (A) Canalicular cholestasis (arrow) with scattered hepatic giant cells containing eight to ten nuclei (asterisks), and (B) a representative portal tract containing two small dilated veins, a small artery, and no recognizable bile ducts. (A and B, hematoxylin and eosin, 132x original magnification).