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Table 4 Ranking of factors for defining incomplete MAS*

From: Algorithm development for corticosteroid management in systemic juvenile idiopathic arthritis trial using consensus methodology

Finding

Ranking (mean)

Level

Definition

CNS dysfunction

N/A

Major

Present

Bleeding/easy bruising/purpura

N/A

Major

Present

Ferritin

5.86

Minor

>5000 ng/ml & increasing

Platelets

5.24

Minor

<150,000/ml or < LLN for lab

PT (INR)

3.52

Minor

>1.2

Fibrinogen

3.52

Minor

<LLN

WBC

3.33

Minor

<LLN

LFT’s

3.10

Minor

>2 XN

d-dimer

3.10

Rejected

 
  1. *1 major and 1 minor or 3 minor are required to meet criteria for diagnosis of incomplete MAS.
  2. LLN lower limit of normal; XN times normal.
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Pediatric Rheumatology

ISSN: 1546-0096