Profiling anti-cyclic citrullinated peptide antibodies in patients with juvenile idiopathic arthritis

Table 5 Sensitivity, specificity, positive and negative predictive values of CCP and/or RF

	All JIA				Polyarticular RF-positive JIA
	Sensitivity	Specificity	PPV	NPV	Sensitivity	Specificity	PPV	NPV
ACPA IgG	0.14	0.98	0.98	0.15	0.73	0.98	0.98	0.86
RF-IgM	0.12	0.92	0.91	0.13	0.93	0.92	0.88	0.96
ACPA IgG and RF IgM	0.07	1.00	1.00	0.14	0.73	1.00	1.00	0.86
ACPA IgG or RF IgM	0.19	0.90	0.95	0.14	0.93	0.90	0.85	0.96

ACPA: anti citrullinated peptide antibody (CCP IgG), RF: rheumatoid factor. PPV: positive predictive value; NPV- negative predictive value.

ISSN: 1546-0096