Figure 2

Aerobic capacity (expressed as Z-score of VO _2peak and VO _2peak /kg) in relation to disease activity in adolescents and young adults with JIA in remission and with active disease. Z scores are compared to age and sex matched healthy controls (* p-values <0.05; **p-values <0.01). Abbreviations: Z-score_: standard deviation of the individual patient compared with values from age- and sex- related historical Dutch controls[37]; VO_{2peak abs}: highest oxygen uptake in liters of oxygen per minute (l/min) during maximum exercise test in l/min; VO_2peak/kg_l : highest oxygen uptake in milliliters of oxygen per kilogram of bodyweight per minute (ml/min/kg) during maximum exercise; AJC: Active Joint Count; DAS28: Disease Activity Score of 28 joints.