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Table 1 Demographics and clinical parameters of paediatric lupus patients and control groups

From: A comparative proteomic study of sera in paediatric systemic lupus erythematosus patients and in healthy controls using MALDI-TOF-TOF and LC MS–A pilot study

Variables

pSLE (N = 40)1

Controls (N = 20)1

p value2

Age (years)

Median

12

13

0.213

Range

5-16

10-15

 

Sex (Female/male)

34/6

15/5

0.326

Disease duration (months)

Median

8

NA

 

Range

1-96

NA

 

SLEDAI score

Median

15

NA

 

Range

4-26

  

Clinical manifestations 1

Cutaneous

25 (62.5)

NA

 

Skin Biopsy

13 (32.5)

NA

 

Renal

24 (60)

NA

 

Renal Biopsy

10 (25)

NA

 

Haematological

18 (45)

NA

 

Oral ulcers

12 (30)

NA

 

Musculoskeletal

12 (30)

NA

 

Neurological

10 (25)

NA

 

Medications used 1

I. Prednisolone

11(27.5)

  

II. Prednisolone and anti-malarials (chloroquine and hydroxychloroquine)

19 (47.5)

  

III. Immunosuppressive therapy 3

10 (25)

  
  1. Abbreviations: SLEDAI SLE disease activity index; Lupus nephritis class based on international society of nephrology/renal pathology society classification criteria (ISN/RPS), NA not applicable, 1 Values are represented as either median & range or Number (percentage): N (%); 2p ≤ 0.05 as significant; 3(methotrexate, azathioprine, mycophenolate mofetil, cyclosporine and cyclophosphamide).