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Table 12 (abstract P209). Patients’ characteristics at baseline

From: Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two

 

Etanercept-cohort

N = 419

Adalimumab -cohort

N = 236

Odd’s ratio#

(95%CI); p

Tocilizumab-cohort

N = 74

Odd’s ratio#

(95%CI); p

Female, n (%)

332 (79.2%)

192 (81.4%)

1.1 (0.7-1.5); 0.78

51 (68.8%)

0.59 (0.38-0.94); 0.027

Age at baseline, mean+/- SD

10.49+/-4.36

11.8 +/-4.0

n.a.; <0.0001

13.90+/-3.63

n.a.; <0.0001

JIA Category n(%)

RF + PA/FR-PA/ExOA

37 (8.8%)/224 (53.5%)/158 (37.7%)

23 (9.7%)/128 (54.2%)/85 (36.0%)

n.s.

9 (12.2%)/47 (63.5%)/18 (24.3%)

0.58 (0.43-0.99); 0.03

First biologic used

400 (95.5%)

122 (51.7%)

0.08 (0.05-0.14); <0.0001

15 (20.2%)

0.02 (0.01-0.03); <0.0001

Co-Med MTX, n(%)

309 (73.7)

127 (53.8)

0.51 (0.37-0.71); <0.0001

34 (45.9)

0.43 (0.26-0.69); 0.0004

JADAS10 [0-40] mean +/-SD

13.8 +/- 7.1

12.1 +/-7.6

n.a.; 0.004

15.1 +/- 7.4

n.s

CHAQ-DI [0-3] mean +/-SD

0.59 +/- 0.6

0.43 +/-0.58

n.a.; <0.0001

0.63+/-0.55

n.s.

Uveitis before start of biologic

23 (5.5%)

59 (25%)

5.73 (3.43-5.99); 0,0001

0

n.a.

  1. # compared to the Etanercept cohort, n.a. not available, n.s. not significant