Volume 6 Supplement 1
Development and initial validation of the parent acceptable symptom state in juvenile idiopathic arthritis (JIA)
© Filocamo et al; licensee BioMed Central Ltd. 2008
Published: 15 September 2008
The parent acceptable symptom state (PASS) constitutes the symptom threshold beyond which parents consider their child' health status as satisfactory. The PASS represents an ambitious target for disease management.
To devise and validate the PASS in patients with JIA.
369 parents completed a multidimensional questionnaire (the JAMAR), including Juvenile Arthritis Functionality Scale (JAFS) (score 0–30), Pediatric Rheumatology Quality of Life (PRQL) questionnaire (score 0–30) and traditional JIA outcome measures, and stated whether they considered their children's status satisfactory or not. PASS thresholds were estimated based on parent opinion and targeting the 75th percentile of cumulative distribution. Stepwise logistic regression was used to assess contributors to PASS. PASS was validated by analyzing proportions of patients who were judged by parent or physician in remission, flare or continued activity.
The PASS threshold
We devised the PASS for JIA. The PASS demonstrated good validity by discriminating strongly between patients in remission or active disease.
This article is published under license to BioMed Central Ltd.