From: Recombinant IL1-RA in the early phase of systemic onset JIA: before the onset of arthritis
Disease mark | Suspected SoJIA patients (without arthritis, n=5) | SoJIA cohort Utrecht (n=15) |
---|---|---|
Spiking fever | 5/5 | 15/15 |
Exanthema | 2/5 | 12/15 |
Arthritis | 0/5 | 15/15 |
CRP (mg/L) | 112±13 | 209±18 |
BSE (mm/hr) | 128±26 | 127±34 |
Ferritin (ug/L) | 937±1118 | 2405±3855 |
MRP8/14 (U/L) | 38490±23077 | 45185±37260 |
IL-18 plasma (ng/L) | 3.6±1.7 | 8.2±9.0 |
Abs. NK cell (x109/L) | 0.096±0.114 | 0.092±0.132 |
NK cell function (% killing) | 4.9±3.7 | 6.5±4.5 |